Supreme Skin Gel

Corrective cult pro-age smoothing serum concentrate - clinically measured for visible wrinkle-depth reduction in 1 hour, with deeper smoothing results after 28 days.¹

150,000+ women trust Biotulin

Inspired by gold-standard invasive wrinkle-smoothing procedures.

Biotulin's iconic at-home pro-age everyday smoothing serum concentrate, clinically measured to visibly reduce mimic-wrinkle depth by −6.8% in 1 hour and −10.4% over 28 days¹:

BENEFITS: Instant & Long-Term Smoothing · Hydration & Plumping · Smoother, Firmer-Looking Skin · Radiant Complexion

TARGETS: Mimic wrinkles · Expression & Fine lines · Dullness · Loss of firmness · Tired-Looking Skin

SUITED TO: All skin types, especially demanding, mature, ageing skin. Kind to sensitive skin that reacts to stronger actives.

Size: 15ml

  • Potent formula with 80% plant-based ingredients, powered by Spilanthol as Biotulin's key smoothing active, with Hyaluronic Acid and Imperata Cylindrica for plumping hydration and lasting moisture.
  • Smooths, plumps and provides long-lasting hydration, yet stays barrier-gentle and kind to sensitive and reactive skin.
  • For ageing mature skin that wants immediate and long-lasting visible pro-age results, without irritation or compromising the skin barrier.

Achieve maximum results with a curated Biotulin Effect Skincare System, using the serum together with the matching your skin type Biotulin cream consistently.

YOUR SKIN TYPE

Supreme Skin Gel

Supreme Skin Gel

-33%
49 € 33 €
Pro-Age Smoothing & Hydration System Starter Set

Pro-Age Smoothing & Hydration System

New to Biotulin
3-week everyday treatment: Starter Set
1 Supreme Skin Gel + 1 Soft Cream · for normal to combination skin
-39%
118 € 72 €
Pro-Age Smoothing & Hydration Signature System Set

Pro-Age Smoothing & Hydration System

Recommended · Consistent use
6-week everyday treatment: Signature Set
2 Supreme Skin Gel + 1 Soft Cream · for normal to combination skin
-35%
167 € 109 €

The Biotulin Effect Formula Science

Supreme Skin Gel is a multifunctional, advanced wrinkle-smoothing, clinically measured serum concentrate, powered by the Biotulin Effect: a pro-age systematic skincare and non-invasive aesthetic science that brings high-performance actives together with a barrier-respecting delivery. Built on the Biotulin Effect formula philosophy:

Clinical Results

Measurably smoother wrinkles in 1 hour & deeper smoothing after 28 days

-6.8%
wrinkle depth · 1 hour
-10.4%
wrinkle depth · after 28 days

Active Ingredients

How to use

DAILY · MORNING & EVENING

  • Apply 1-2 pumps after cleansing, spread evenly on face and neck
  • Focus on deep expression wrinkles
  • Follow with your Biotulin cream

For long-lasting results, use monthly as an intensive morning and evening pro-age corrective concentrate:

1 bottle: approx. 3-week system
2 bottles: approx. 6-week intensive cycle
3 bottles: approx. 12-week intensive cycle

Biotulin non-invasive aesthetic pro tip: reapply on the go as an instant smoothing perfector before meetings, events, travel or photography, or any time you want to look fresh.

All Ingredients

Quality Satisfaction Guarantee

100% vegan ● paraben free ● silicone free

In consumer testing

After After
Before Before

Key benefits

Why women with visible signs of ageing choose Supreme Skin Gel Serum Concentrate

Clinically Measured Instant Visible Mimic Wrinkles Smoothing

Clinically measured to visibly smooth the appearance of expression lines within 60 minutes, for skin that looks fresher, smoother and more refined.

Clinically Measured Long-Term Effect: Progressive Wrinkle Refinement

With consistent twice-daily use, the visible smoothing effect deepens over 28 days, supporting smoother-, firmer-looking skin.

Firmer-, Fresher-Looking Skin

Helps improve the look of skin firmness, smoothness and refinement while preserving natural expression.

Barrier-friendly, non-irritating, retinol-free

Intense Long-Lasting Hydration & Plumping

Hyaluronic Acid and Imperata Cylindrica help deeply hydrate, plump the look of skin and lock in lasting moisture.

Invasive Aesthetic-Inspired Everyday Correction

Inspired by aesthetic wrinkle-smoothing treatments, reinterpreted as a potent at-home corrective serum concentrate.

80% Plant-Based, 100% Vegan, Performance Crafted in Germany

30-Day Satisfaction Guarantee

Try Supreme Skin Gel at home for 30 days. Only keep it if you are completely convinced.

The Biotulin Effect Powered by Three Plant-Derived Actives

One smart performance formula for instant and long-lasting smoothing, hydration and skin refinement.

Hyaluronic Acid: Deep hydration with instant plump. This moisture magnet keeps your skin supple, dewy, and fresh from morning to night.

Imperata Cylindrica: This desert plant locks in moisture to prevent moisture loss. Think long-lasting hydration, even in the harshest conditions.

Trusted by 150,000+ Women

Visible smoothing. Real pro-age skincare system. Real visible results.

Among Biotulin Community, there were as well, over the years, names admired internationally for taste and intelligence, that have been reported to choose Biotulin‘s Supreme Skin Gel, drawn to visible results that keep skin looking naturally youthful.

HIGH-PERFORMANCE SKINCARE, INSPIRED BY INVASIVE AESTHETIC CARE

A corrective everyday concentrate combining the ease of daily skincare with aesthetic-inspired visible performance.

Biotulin's Supreme Skin Gel Smoothing Serum Concentrate
Biotulin's Supreme Skin Gel Smoothing Serum Concentrate
Classic Pro-Age Smoothing Serums & Ampoules
Classic Pro-Age Smoothing Serums & Ampoules
In-Clinic Wrinkle-Smoothing Procedures
In-Clinic Wrinkle-Smoothing Procedures
Immediate effect in 1 hr ~ Variable ~ Variable
Reapply on the go, touch-up anytime ~ Limited ✕
Gentle to the skin barrier ~ Variable ~ Variable
Non-sticky, comfortable texture ~ Variable ✕
Lightweight daily skincare ✓ ✕
At-home, no appointment needed ✓ ✕
Visible smoothing effect ~ Variable ✓
Preserves natural facial expression ✓ ~ Often no

Complete your Biotulin Effect

Supreme Skin Gel

Your smoothing serum concentrate

Day & Night

Supreme Skin Gel
Supreme Skin Gel
Regular price
33,00 €
Sale price
33,00 €
Regular price
49,00 €

Choose Your Curated Biotulin Effect System

Specially curated skincare sets with Supreme Skin Gel Serum Concentrate for your individual needs, designed to help maximise visible results.

Pro-Age Smoothing & Hydration System Starter Set

Normal to Combination Skin

72,00 €118,00 € 4.8

Pro-Age Smoothing & Hydration Signature System Set

Normal to Combination Skin

109,00 €167,00 € 4.7
Supreme Skin Gel
Supreme Skin Gel
49,00 €33,00 €