ReelUp tracking pixel Read the Privacy Policy
Skip to content

Free Travel Size Pro Age Travel Kit with orders from €50

Free US shipping on orders over 50€

30-Day Refund Guarantee

Supreme Skin Gel

Corrective cult pro-age smoothing serum concentrate - clinically measured for visible wrinkle-depth reduction in 1 hour, with deeper smoothing results after 28 days.¹ 

Over 150.000 women trust Biotulin

Inspired by gold-standard invasive wrinkle-smoothing procedures. Biotulin's iconic dual-action pro-age smoothing serum concentrate for daily use and targeted on-the-go wrinkle touch-up.

BENEFITS: Instant & Long-Term Smoothing · Hydration & Plumping · Smoother & Firmer-Looking Skin · Radiant Complexion

TARGETS: Mimic Wrinkles · Expression & Fine Lines · Dullness · Loss of Firmness · Tired-Looking Skin

SUITED TO: All skin types, especially mature skin, including sensitive skin. 

  • Potent 100% plant-based formula powered by Spilanthol, Hyaluronic Acid and Imperata Cylindrica
  • Smooths, plumps and provides long-lasting hydration, yet stays barrier-gentle and kind to sensitive skin.

Achieve maximum results with a curated Biotulin Effect Skincare System, using the serum together with the matching your skin type Biotulin cream consistently. 

YOUR SKIN TYPE

Supreme Skin Gel

Supreme Skin Gel

-33%
49 € 33 €
Biotulin Effect Pro-Age Smoothing & Hydration System

Pro-Age Smoothing & Hydration System

New to Biotulin
3-week everyday treatment: Starter Set
1 Supreme Skin Gel + 1 Soft Cream · for normal to combination skin
-39%
118 € 72 €
BIOTULIN EFFECT Pro-Age Smoothing & Hydration Signature System Set

Pro-Age Smoothing & Hydration System

Recommended · Consistent use
6-week everyday treatment: Signature Set
2 Supreme Skin Gel + 1 Soft Cream · for normal to combination skin
-17%
167 € 139 €

The Biotulin Effect Formula Science

Supreme Skin Gel is a multifunctional, advanced wrinkle-smoothing, clinically measured serum concentrate, powered by the Biotulin Effect: a pro-age systematic skincare and non-invasive aesthetic science that brings high-performance actives together with a barrier-respecting delivery. Built on the Biotulin Effect formula philosophy:

Clinical Results

Measurably smoother wrinkles in 1 hour & deeper smoothing after 28 days

-6.8%
wrinkle depth · 1 hour
-10.4%
wrinkle depth · after 28 days

Active ingredients

How to use

Dual action use

  • Daily full face serum concentrate: Apply 1-2 pumps morning and evening after cleansing, spread evenly on face and neck. Follow with your Biotulin cream.
  • Targeted smoothing touch up: Reapply throughout the day on visible mimic wrinkles whenever needed.

Then keep the treatment duration on a monthly basis below :

1 bottle: approx. 3-week system
2 bottles: approx. 6-week intensive cycle

BIOTULIN NON-INVASIVE PRO TIP: reapply before meetings, events, travel or photography, or any time you want a fresher, smoother looking finish.

Ingredient list

MONEY-BACK GUARANTEE

100% vegan ● paraben free ● silicone free

In consumer testing

After After
Before Before

Key benefits

Why women with visible signs of ageing choose Supreme Skin Gel Serum Concentrate

Clinically Measured Instant Wrinkle Smoothing in 1 Hour

Progressive Wrinkle Refinment with continued use

Firmer-, Fresher-Looking Skin

Barrier-friendly & non-irritating

Long-Lasting Hydration & Plumping

dual-action use. inspired by gold-standard aesthetic treatments

80% Plant-Based, 100% Vegan. german skincare expertise

30-Day Satisfaction Guarantee

The Biotulin Effect Powered by Three Plant-Derived Actives

One smart performance formula for instant and long-lasting smoothing, hydration and skin refinement.

Hyaluronic Acid: Deep hydration with instant plump. This moisture magnet keeps your skin supple, dewy, and fresh from morning to night.

Imperata Cylindrica: This desert plant locks in moisture to prevent moisture loss. Think long-lasting hydration, even in the harshest conditions.

Trusted by 150,000+ Women

Visible smoothing. Real pro-age skincare system. Real visible results.

Among Biotulin Community, there were as well,  over the years, names admired internationally for taste and intelligence, that have been reported to choose Biotulin‘s Supreme Skin Gel, drawn to visible results that keep skin looking naturally youthful. 

A new standard in everyday wrinkle-smoothing care High-performance skincare, inspired by aesthetic care

High-performance skincare, inspired by aesthetic treatments

A corrective everyday concentrate combining the ease of daily skincare with aesthetic-inspired wrinkle smoothing performance.

Skin Gel
Skin Gel
Ampoules
Ampoules
Injectables
Injectables
Immediate effect in 1 hr ~ Variable ~ Variable
Reapply on the go, touch-up anytime ~ Limited
Gentle to the skin barrier ~ Variable ~ Variable
Non-sticky, comfortable texture ~ Variable
Lightweight daily skincare
At-home, no appointment needed
Visible smoothing effect ~ Variable
Preserves natural facial expression ~ Often no

Your skin routine

Cleanse and refresh

Start by dampening your face with warm water. Apply a small amount of the cleanser to your hands and gently massage it onto your face in circular motions, focusing on areas with impurities or makeup. Rinse thoroughly with warm water and pat dry with a clean towel.

B*Clean All-In-One Cleansing & Smoothing Micellar Water
B*Clean All-In-One Cleansing & Smoothing Micellar Water
Regular price
19,00 €
Sale price
19,00 €
Regular price
29,00 €

Choose Your Curated Biotulin Effect System

Specially curated skincare sets with Supreme Skin Gel Serum Concentrate for your individual needs, designed to help maximise visible results.